Li, Yung-Hua

Phone: (902) 494-3063

Email: yung-hua.li@dal.ca

Associate Professor, Department of Applied Oral Sciences

Academic Credentials:
PhD (UM), MSc (UM), DMD (WU)
Professional Appointments:
Cross Appointment, Department of Microbiology and Immunology, Faculty of Medicine
Personal Website:



Tian XL, Salim H, Rutherford H, Dong GF, LI YH. (2018). Double blocking the UppP- and DgK-catalyzed pathways involved in the biosynthesis or recycling of lipid carrier completely inhibits the growth of Streptococcus mutans. AMMI Annual Conference-2018. Vancouver, BC. Canada, May 2-5, 2018.

Tian XL, Cyr K, Huang XX, LI YH. (2017) A New Pheromone-Guided Antimicrobial Peptide HP30 for Targeted Killing of Streptococcus mutans in mixed culture biofilms. International Conference on Microbial Pathogenesis and Infection Control. Toronto, Ontario, Canada, Aug 22-24, 2017.

Li, YH, Ropson D, Dugandzic A, Tian XL. (2017). The BceABRS Four-Component System Essential for Bacitracin Sensing and Response is Required for Biofilm Formation and Virulence of Streptococcus mutans. International Conference on Microbial Pathogenesis and Infection Control. Toronto, Ontario, Canada, Aug 22-24, 2017.

Tian XL, Dong GF, Salim H, Li YH. (2017). Structural and functional analysis of a bacterial quorum-sensing signal peptide receptor protein. The 31st Annual Symposium of the Protein Society. Montreal, QB, Canada, July 24-27, 2017.

Li, YH, Tian XL, Dong GF, Huang XX. (2017) Regulated Proteolysis of the Alternative Sigma Factor SigX During Bacterial Competence Development. The 31st Annual Symposium of the Protein Society. Montreal, QB, Canada, July 24-27, 2017.

Li YH, Tian XL. Targeted regulation of oral microbial ecology in an in vitro biofilm community. BIT’s 7th World Gene Convention-2016. Shanghai, China, Nov. 3-5, 2016.

Li YH, Tian XL, Cyr K, Liu TL, Tziolas G, Slime H. Quorum sensing-mediated social cooperation is required for Streptococcus mutans to compete with related species in biofilms. ASM Microbe-2016, Boston, USA, June 16-20, 2016.

Tian XL, Dong GF, Cyr K, Liu, TL, Lin W, Tziolas G, Li YH. Structural and functional insights into the ComD histdine protein kinase, a quorum sensing signal peptide receptor of Streptococcus mutans. ASM Microbe-2016, Boston, USA, June 16-20, 2016.

XL Tian, GF Dong, M Parcells, YH Li. Peptide antibiotics modulate transcriptional changes and virulence expression in Streptococcus mutans. Poster A-1199, The 54th International Conference on Antimicrobial Agents and Chemotherapy (ICAAC), ASM. Washington D.C. September 2014.

YH Li, N Jalal, XL Tian, GF Dong, M Parcells. Identification and characterization of SMU.244 encoding a protein required for resistance to cell wall-acting antibiotics in Streptococcus mutans. The 54th International Conference on Antimicrobial Agents and Chemotherapy (ICAAC), ASM. Washington D.C. September 5-9, 2014.

Tian XL, Liu TL, Li YH. Quorum sensing regulation of the bacteriocin production in Streptococcus mutans: cooperation or/and competition? The 62th Annual Conference of the Canadian Society of Microbiologists, UBC, Vancouver, BC, June 20-23, 2012. Abstract #II058

Jalal NA, Tian XL, LI YH. Genetic and phenotypic analysis of a novel gene involved in the cell wall biosynthesis and resistance to bacitracin in Streptococcus mutans. IHRTP Graduate Student Research Day. Dalhousie University, May 15, 2012

LI YH
, Tian XL. 2011. Rational development of novel pheromone-guided antimicrobial peptides against Streptococcus mutans. BIT’s 1st Annual Symposium of Antimicrobial Research (SAR-2011). Beijing, China. Dec. 1-3, 2011.

Tian XL, German M, Gong YX, Ouyang J, LI YH. 2011. The innate defense peptides activate the BceABRS four-component system that regulates bacitracin resistance in Streptococcus mutans. 61st Annual Conference of the Canadian Society of Microbiologists, CSM, St. John’s, Newfoundland, June 20-23, 2011.